&lt;p&gt;Ultrasound is the only medical imaging modality on the International Space Station due to its size, power requirements and versatility in medical imaging.&amp;nbsp; Unfortunately, ultrasound is&amp;nbsp;a very operator dependent procedure and astronauts&amp;nbsp;do not have&amp;nbsp;time to train sufficiently before flight.Virtual Guidance, a type of just in time training, is a method to facilitate autonomous operation of medical ultrasound by untrained astronauts with an audio/video tutorial.&amp;nbsp; On the International Space Station, astronauts have to be guided through ultrasound studies by experts on the ground.&amp;nbsp; This method is called remote guidance, and&amp;nbsp;has been very successful with communication time delays of&amp;nbsp;2 seconds or less.&amp;nbsp; On missions further from earth, remote guidance will not be possible.&amp;nbsp; Virtual Guidance streams an audio video tutorial to the astronaut through video glasses actually while they are performing the ultrasound study.&amp;nbsp; The tutorial includes step by step instructions in patient positioning, equipment use, how to hold the probe, scanning protocols and required images.&amp;nbsp; For each required image, there is a photograph of the probe location, a representative ultrasound image from the site and audio instructions in how to achieve the view.&amp;nbsp; In addition, there is a section for each required view that covers what can go wrong.&amp;nbsp; This includes images from incorrect locations and how to improve the image to achieve the required results.&amp;nbsp; Virtual guidance has demonstrated successful imaging of the eye and carotid artery.&amp;nbsp; This project builds upon previous successes with Virtual Guidance by incorporating Augmented Reality, in the form of a 3-dimensional anatomical image,&amp;nbsp;improving the astronaut&amp;rsquo;s situational awareness. Untrained ultrasound operators will be recruited in the future to perform Focused Assessment with Sonography in Trauma (FAST) exams using only the Virtual Guidance audio/video tutorial. The quality of the resulting Images will be evaluated by an external expert.&lt;/p&gt;